I like to have Find Fish active when I'm in my fishing gear, and my main gathering skill active when I'm geared normally. I found that this helps me a lot with the new Equipment Manager:
1. Create two new sets - your main gear set (call it Main) and your fishing set (call it Fishing)
2. Create the following two macros (use the '?' icon for them; it's the first icon on the list):
#showtooltip [your main weapon name here]
/equipset Main
/cast Find Herbs (or Find Minerals, or whatever)
#showtooltip [your fishing pole name here]
/equipset Fishing
/cast Find Fish
When I say "your main weapon name here" or "your fishing pole name here", I mean replace the bracketed area with the exact name of your weapon or pole... e.g. "#showtooltip Mastercraft Kalu'ak Fishing Pole"
3. Save these two macros, call one 'Main' and the other 'Fishing', and place them on your toolbar. Ta-da, you can now easily switch from fighting to fishing with the click of a button!